Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report

Authors

  • Norny Syafinaz Ab Rahman Sustainable Initiative towards Healthy Living and Environment for Sejahtera Community (SITEC) Flagship, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia. https://orcid.org/0000-0001-8358-0925
  • Nur Alyaa Anisa Mat Harom Kulliyyah of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia.
  • Nor Ilyani Mohamed Nazar Sustainable Initiative towards Healthy Living and Environment for Sejahtera Community (SITEC) Flagship, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, 25200 Kuantan, Pahang, Malaysia. https://orcid.org/0000-0002-7508-9420

Keywords:

Home medication review, medication management therapy, medication adherence, chronic diseases, rural areas

Abstract

Introduction: Home Medication Review (HMR) is crucial for optimising medication use and improving patient’s outcomes. Despite its potential benefits, HMR implementation in rural areas faces challenges. This study evaluates the impact of HMR programs on patients with chronic diseases in a rural setting, addressing challenges and proposing strategies for improvement. Case Presentations: This case report presents two cases involving patients with chronic diseases residing in a rural area of Pahang, Malaysia, who participated in pharmacist-led HMR visits. The first case describes a 62-year-old single Malay female with multiple chronic conditions, including Type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, and bronchial asthma, managed with eight prescribed medications. The second case involves a 34-year-old married Malay female diagnosed with hypertension and T2DM, receiving nine prescribed medications. Both patients underwent a follow-up HMR visit six months after the initial consultation. During each visit, assessments included blood pressure (BP), pulse rate (PR), and blood glucose tests. HMR activities encompassed medication reconciliation, review, patient interviews, evaluation of medication knowledge and adherence, inspection of medication storage, and patient counseling. Identified drug-related problems (DRPs) were addressed through appropriate interventions. Results: The study reveals improved patient understanding post-HMR and emphasising the role of pharmacists in addressing medication-related issues. Challenges like non-adherence, uncontrolled disease conditions, and incorrect insulin storage persist. The discussion explores these challenges, citing the need for patient education, regular follow-ups, multidisciplinary collaboration, and technology integration to enhance patient outcomes. Summary: These cases underscore the challenges of managing chronic diseases in resource-limited rural settings and highlight the critical role of pharmacist-led HMR in optimizing medication use and improving patient outcomes. The findings highlight the importance of regular follow-up, tailored interventions to address drug-related problems, and collaborative care approaches. They also advocate for integrating technology, enhancing patient education, and addressing social determinants to improve medication understanding and overall health outcomes in underserved populations.

References

Agency for Healthcare Research and Quality. (2018). Guide to Improving Patient Safety in Primary Care Settings by Engaging Patients and Families. Content last reviewed April 2018., Rockville, MD. https://www.ahrq.gov/patient-safety/reports/engage/strategies.html

Anawade, P. A., Sharma, D., Gahane, S. (2024) A Comprehensive Review on Exploring the Impact of Telemedicine on Healthcare Accessibility. Cureus, 16(3): e55996. DOI 10.7759/cureus.55996.

Ang, W.C., Lah, J. C., Zulkepli, N., Syukri, N., & Rosedi, A. (2022). Carers’ Perspectives on Home Medication Review by a State Hospital in Malaysia, International Journal of Care Scholars, 5(1),49-55. https://journals.iium.edu.my/ijcs/index.php/ijcs/article/view/236

Bingham, J. M., Black, M., Anderson, E. J., Li, Y., Toselli, N., Fox, S., Martin, J. R., Axon, D. R., Silva-Almodóvar, A. (2021). Impact of Telehealth Interventions on Medication Adherence for Patients with Type 2 Diabetes, Hypertension, and/or Dyslipidemia: A Systematic Review. Annals Pharmacotherapy, 55(5), 637-649. doi: 10.1177/1060028020950726. Epub 2020 Aug 20. PMID: 32815400.

Brown, M. T., & Bussell, J. K. (2011). Medication adherence: WHO cares? Mayo Clin Proc, 86(4), 304-14. doi: 10.4065/mcp.2010.0575. Epub 2011 Mar 9. PMID: 21389250; PMCID: PMC3068890.

Brugts, J. J., Arima, H., Remme, W., Bertrand, M., Ferrari, R., Fox, K., DiNicolantonio, J., MacMahon, S., Chalmers, J., Zijlstra, F., Caliskan, K., Simoons, M. L., Mourad, J. J., Boersma, E., & Akkerhuis, K. M. (2014). The incidence and clinical predictors of ACE-inhibitor induced dry cough by perindopril in 27,492 patients with vascular disease. International Journal of Cardiology, 176(3), 718–723. https://doi.org/10.1016/j.ijcard.2014.07.108

Chandrasekhar, D., Joseph, E., Ghaffoor, F. A., & Thomas, H. M. (2019). Role of pharmacist led home medication review in community setting and the preparation of medication list. Clinical Epidemiology and Global Health, 7(1), 66–70. https://doi.org/10.1016/j.cegh.2018.01.002

Cochran, A. L., McDonald, N. C., Prunkl, L., Vinella-Brusher, E., Wang, J., Oluyede, L., Wolfe, M. (2022). Transportation barriers to care among frequent health care users during the COVID pandemic. BMC Public Health, 22(1), 1783. doi: 10.1186/s12889-022-14149-x. PMID: 36127650; PMCID: PMC9486769.

Diabetes Disaster Response Coalition. [Last accessed on 2025 Jan 14]. Available from: https://diabetes.org/sites/default/files/2023-10/ddrc-storing-insulin-2018.pdf

Dhillon, A. K., Hattingh, H. L., Stafford, A., & Hoti, K. (2015). General practitioners’ perceptions on home medicines reviews: a qualitative analysis. BMC Family Practice, 16(1). https://doi.org/10.1186/s12875-015-0227-8

Fitria, N., Lailaturrahmi, L., Sari, Y. O., Anata, F. T., & Husnia, K. (2023). Adherence Assessment on Hypertension Therapy Using the Pill Count Method In Lubuk Kilangan Health Center, Indonesia. Jurnal Sains Farmasi & Klinis, 10(1), 28–34. https://doi.org/10.25077/jsfk.10.1.28-34.2023

Goh, B. Q., Tay, A. H. P., Khoo, R. S. Y., Goh, B. K., Lo, P. F. L., & Lim, C. J. F. (2014). Effectiveness of Medication Review in Improving Medication Knowledge and Adherence in Primary Care Patients. Proceedings of Singapore Healthcare, 23(2), 134–141. https://doi.org/10.1177/201010581402300207

Gudi, S. K., Kashyap, A., Chhabra, M., Rashid, M., & Tiwari, K. K. (2019). Impact of pharmacist-led home medicines review services on drug-related problems among the elderly population: a systematic review. Epidemiology and Health, 41, e2019020. https://doi.org/10.4178/epih.e2019020

Guideway Care. (2023, November 8). Guideway Care ranked number 83 fastest-growing company in North America on the 2023 Deloitte Technology Fast 500™. BusinessWire. https://www.businesswire.com/news/home/20231108916913/en/Guideway-Care-Ranked-Number-83-Fastest-Growing-Company-in-North-America-on-the-2023-Deloitte-Technology-Fast-500%E2%84%A2

Hanjani, L. S., Bell, J. S., & Freeman, C. (2020). Undertaking medication review by telehealth. Australian Journal of General Practice, 49(12), 826–831. https://doi.org/10.31128/ajgp-06-20-5461

Hanley, J., Fairbrother, P., McCloughan, L., et al. (2015). Qualitative study of telemonitoring of blood glucose and blood pressure in type 2 diabetes. BMJ Open, 5:e008896. doi:10.1136/bmjopen-2015008896

Jacob, J. J. (2023). Insulin Storage Guidance for Patients with Diabetes Using Insulin. Indian J Endocrinol Metab, 27(2), 93-95. doi: 10.4103/2230-8210.374161. Epub 2023 Apr 14. PMID: 37292077; PMCID: PMC10245305.

Lee, J. K., Grace, K. A., Taylor, A. J. (2006). Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial. JAMA, 6, 296(21), 2563-71. doi: 10.1001/jama.296.21.joc60162. Epub 2006 Nov 13. PMID: 17101639.

Mégarbane, B., Chevillard, L., Nihel Khoudour, & Declèves, X. (2021). Gliclazide disposition in overdose – a case report with pharmacokinetic modeling. Clinical Toxicology, 60(4), 541–542. https://doi.org/10.1080/15563650.2021.1993245

Nasser, J., Al Aradi, K., Ebrahim, K. S., Omran, A. (2018). High incidence of cough users of Angiotensin-Converting Enzyme Inhibitors. Bahrain Med Bull, 40(2), 97-99.

Newman, T. V., San-Juan-Rodriguez, A., Parekh, N., Swart, E. C. S., Klein-Fedyshin, M., Shrank, W. H., Hernandez, I. (2020). Impact of community pharmacist-led interventions in chronic disease management on clinical, utilization, and economic outcomes: An umbrella review. Res Social Adm Pharm, 16(9), 1155-1165. doi: 10.1016/j.sapharm.2019.12.016. Epub 2020 Jan 14. PMID: 31959565.

Ofman, J. J., Badamgarav, E., Henning, J. M., Knight, K., Gano, A. D., Levan, R. K., Gur-Arie, S., Richards, M., Hasselblad, V., & Weingarten, S. (2004). Does disease management improve clinical and economic outcomes in patients with chronic diseases? A systematic review. The American Journal of Medicine, 117(3), 182–192. https://doi.org/10.1016/j.amjmed.2004.03.018

Patounas, M., Lau, E. T., Chan, V., Rigby, D., Kyle, G. J., Khatri, J., Poudel, A., & Nissen, L. M. (2021). Home medicines reviews: a national survey of Australian accredited pharmacists’ health service time investment. Pharmacy Practice, 19(3), 2376. https://doi.org/10.18549/pharmpract.2021.3.2376

Rahman, M., White, E. M., Thomas, K. S., & Jutkowitz, E. (2020). Assessment of Rural-Urban Differences in Health Care Use and Survival Among Medicare Beneficiaries With Alzheimer Disease and Related Dementia. JAMA Network Open, 3(10), e2022111. https://doi.org/10.1001/jamanetworkopen.2020.22111

Ravindra, B. N., & Kaushik, A. (2022). Effect of Pharmacy Home Medications Review Services On Drug-Related Issues Among The Elderly Population. International Journal of Advance and Applied Research, 10(1), 1306–1315. https://doi.org/10.5281/zenodo.8017181

Richter, B., Bongaerts, B., Metzendorf, M-I. (2023). Thermal stability and storage of human insulin. Cochrane Database of Systematic Reviews, Issue 11. Art. No.: CD015385. DOI: 10.1002/14651858.CD015385.pub2.

Rosli, M. R., Neoh, C. F., Wu, D., Hassan, N. W., Mahmud, M., Rahimi, A., & Karuppannan, M. (2021). The evaluation of home medication review for patients with type 2 diabetes mellitus by community pharmacists: A randomised controlled trial. Pharmacy Practice (Internet), 19(3), 2397.https://doi.org/10.18549/pharmpract.2021.3.2397

Rothwell, M., & Hogan, A. (2015). Clinical pharmacists connecting with patients in rural and remote towns via telehealth. 13th National Rural Health Conference, Darwin Convention Centre, NT, Australia.

https://www.ruralhealth.org.au/13nrhc/images/paper_Rothwell,%20Michelle.pdf

Sabaté, E., ed. (2003). Adherence to Long-Term Therapies: Evidence for Action. Geneva, Switzerland: World Health Organization.

Saqib, A., Atif, M., Ikram, R., Riaz, F., Abubakar, M., & Scahill, S. (2018). Factors affecting patients’ knowledge about dispensed medicines: A Qualitative study of healthcare professionals and patients in Pakistan. PLOS ONE, 13(6), e0197482. https://doi.org/10.1371/journal.pone.0197482

Sari, Y. O., Permatasari, D., Mariza, W., Fitria, N., & Lailiani, R. (2023). Application of Home Medication Review (HMR) on Patient Adherence in Type 2 Diabetes Mellitus (T2DM) Blood Sugar Management. JSFK (Jurnal Sains Farmasi & Klinis), 9(sup), 160–167. https://doi.org/10.25077/jsfk.9.sup.160-167.2022

Sundus, A., Pin, T., & Sellappans, R. (2022). What Do Older Adults and Their Caregivers in Malaysia Think of Home Medication Review? A Qualitative Inquiry. Malaysian Journal of Medicine and Health Sciences, 18(1), 2636–9346. https://expert.taylors.edu.my/file/rems/publication/108546_8462_2.pdf

Sundus, A., Sellappans, R., Pin, T. M. (2024). Informing policy makers in developing countries: Practices and limitations of geriatric home medication review in Malaysia-A qualitative inquiry. Asian Pac J Trop Med, 17(1), 21-29.

Tan, Y. M., Chong, C. P., & Cheah, Y. C. (2019). Impact of hospital pharmacist-led home medication review program for people with schizophrenia: A prospective study from Malaysia. Journal of Applied Pharmaceutical Science, 9(7), 034-041.

Tampa’i, R., Sumombo, J., Hariyadi, H., Lengkey, Y. (2021). Gambaran Drug Related Problems (DRPs) pada Pasien Diabetes Melitus Tipe 2 di Puskesmas Tuminting. Jurnal Kefarmasian Indonesia, 11(1), 49–55. https://doi.org/10.22435/jki.v11i1.3499

Trief, P. M., Cibula, D., Rodriguez, E., Akel, B., & Weinstock, R. S. (2016). Incorrect Insulin Administration: A Problem That Warrants Attention. Clinical Diabetes, 34(1), 25–33. https://doi.org/10.2337/diaclin.34.1.25

Yilmaz, I. (2019). Angiotensin-Converting Enzyme Inhibitors Induce Cough. Turkish Thoracic Journal, 20(1), 36–42. https://doi.org/10.5152/turkthoracj.2018.18014

Downloads

Published

2025-01-31

How to Cite

Ab Rahman, N. S., Mat Harom, N. A. A., & Mohamed Nazar, N. I. (2025). Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report. Journal of Pharmacy, 5(1), 73–82. Retrieved from https://journals.iium.edu.my/ktn/index.php/jp/article/view/326

Issue

Section

Original Articles

Most read articles by the same author(s)

1 2 > >>