Complete Hydatidiform Mole and Co-Existing Foetus with Severe Maternal Thyrotoxicosis: A Case Report

Authors

  • Shu Khien Thong Ministry of Health Malaysia
  • Nur Zawani Zainon International Islamic University Malaysia
  • Nur Rashidah Abd Malik International Islamic University Malaysia
  • Izzni Adilah Dzulkifli International Islamic University Malaysia
  • Amira Anis Ali Yeon International Islamic University Malaysia
  • Mohd Azam Mohd Yusoff International Islamic University Malaysia
  • Azliana Abd. Fuaat International Islamic University Malaysia
  • Hamizah Ismail International Islamic University Malaysia

DOI:

https://doi.org/10.31436/imjm.v25i03.2892

Keywords:

Hydatidiform mole, complete hydatidiform mole with normal co-twin, CHMCF, twin molar pregnancy

Abstract

Twin molar pregnancy refers to the coexistence of a complete or partial hydatidiform mole alongside a foetus. A complete hydatidiform mole with co-existing foetus (CHMCF) is an exceptionally rare obstetric phenomenon, with an incidence of approximately 1 in 20,000 to 100,000 pregnancies. Owing to its rarity, no standardized management guidelines currently exist.  We report a case of a 33-year-old woman, G5P4, diagnosed with CHMCF at 15 weeks gestation, who developed severe maternal thyrotoxicosis and rapid uterine enlargement necessitating termination of pregnancy for maternal safety. Following termination of pregnancy, she was monitored closely with β-hCG surveillance due to the potential risk of gestational trophoblastic neoplasia. This case highlights the diagnostic dilemma, as well as challenges of management and post-treatment surveillance in CHMCF. Early diagnosis and multidisciplinary care are essential for optimal maternal outcomes.

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Published

01.07.2026

How to Cite

Thong, S. K., Zainon, N. Z., Abd Malik, N. R., Dzulkifli, I. A., Ali Yeon, A. A., Mohd Yusoff, M. A., Abd. Fuaat, A., & Ismail, H. (2026). Complete Hydatidiform Mole and Co-Existing Foetus with Severe Maternal Thyrotoxicosis: A Case Report . IIUM Medical Journal Malaysia, 25(03). https://doi.org/10.31436/imjm.v25i03.2892

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