Central Nervous System Tumour in Pregnancy, a Diagnostic Challenge or Management Quandary

Authors

  • Nur Rashidah Abd Malik International Islamic University Malaysia
  • Hamizah Ismail International Islamic University Malaysia
  • Amira Anis Ali Yeon International Islamic University Malaysia
  • Nurul Nafizah Mohd Rashid International Islamic University Malaysia
  • Mohd Ghaddafi Wahab International Islamic University Malaysia
  • Mohamed Saufi Awang Sultan Ahmad Shah Medical Centre, International Islamic University Malaysia

DOI:

https://doi.org/10.31436/imjm.v25i02.2685

Keywords:

CNS tumour, central nervous system tumour, pregnancy

Abstract

Central nervous system (CNS) tumour, being rare in pregnancy, posed different challenges. We report three challenging cases managed at our centre. The first case was a diagnostic puzzle, bringing a myriad of differentials since the eighth week of gestation. Diagnosis made after magnetic resonance imaging (MRI) post-delivery at 35 weeks of gestation led to cervical spine meningioma excision surgery and subsequent progressive, remarkable neurologic recovery. Two additional cases were not a diagnostic mystery, yet they posed management challenges. The second case was diagnosed with a cerebellar tumour complicated with hydrocephalus at a pre-viable gestation. Pregnancy was able to be prolonged up to viability at extreme prematurity at 26 weeks when she needed delivery with subsequent cerebellar haemangioma excision and recovery. However, the third case became pregnant during follow-up after radiation therapy for brain glioma, with persistent symptoms necessitating termination of pregnancy.

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Published

01.04.2026

How to Cite

Abd Malik, N. R., Ismail, H., Ali Yeon, A. A., Mohd Rashid, N. N., Wahab, M. G., & Awang, M. S. (2026). Central Nervous System Tumour in Pregnancy, a Diagnostic Challenge or Management Quandary . IIUM Medical Journal Malaysia, 25(02). https://doi.org/10.31436/imjm.v25i02.2685

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