Prevalence of Breast Cancer and Its Associated Factors for Recurrence in Hospital Tengku Ampuan Afzan 2008 – 2012

Authors

  • Azhani Chik

DOI:

https://doi.org/10.31436/imjm.v18i2.646

Abstract

Introduction: Breast cancer is the commonest malignancy in Malaysian women. Cancer recurrence has been a detrimental factor towards survival with peak of recurrence recorded in first 2 years of diagnoses. Identifying the prognostic factors towards recurrence is important to management and prolonging survival. Materials and method: We have retrospectively analyzed 179 patients women with breast cancer based on 5 years single centre database with minimum follow up of 2 years. The demographic and clinicopathological characteristics were determined using descriptive statistics. Survival were calculated based on Kaplan- Meier method and multivariate analysis by Cox proportional hazards was performed to evaluate the potential factors affecting breast cancer recurrence. Results: Mean follow up was 42 months, with mean age 52 years and 60.9% presented in Stage II disease. Overall recurrence was 41.9% with local recurrence 2.1%, regional recurrence 12.3% and distant recurrence 27.4%. 50% of our patients developed recurrence at 25 months. In univariate analysis, time to first presentation was significantly correlated with recurrence. However, in multivariate analysis; tumor size, lymph node positivity  and lymphovascular invasion were independently associated with recurrence. Conclusion: Even though local data on breast cancer recurrence is sparse, it does correlate with the international data. Thus, optimizing our care in breast cancer.

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Published

2020-01-15

How to Cite

Chik, A. (2020). Prevalence of Breast Cancer and Its Associated Factors for Recurrence in Hospital Tengku Ampuan Afzan 2008 – 2012. IIUM Medical Journal Malaysia, 18(2). https://doi.org/10.31436/imjm.v18i2.646