Subcutaneous Panniculitis-like T-cell Lymphoma: A Case Report of A Solved Conundrum

Authors

  • Khairul Bariah Chi Adam International Islamic University Malaysia
  • Nabilah Rashida Jamali International Islamic University Malaysia
  • Nor Adilah Harun International Islamic University Malaysia
  • Nor Aszlitah Burhanudin International Islamic University Malaysia
  • Asmah Hanim Hamdan International Islamic University Malaysia

DOI:

https://doi.org/10.31436/imjm.v23i01.1985

Keywords:

Lymphoma, Facial, Swelling, Subcutaneous, Panniculitis

Abstract

Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare primary cutaneous lymphoma which often be very complexed to be diagnosed. Here we reported a case of a 38-year-old lady with wax and wane course of left facial swelling associated with prolonged pyrexia of unknown origin, lethargy and prominent weight loss. Multiple investigations were conducted to reach to the conclusive diagnosis. Histopathological showed infiltration of neoplastic lymphoid cells within the adipocyte clusters with hyperchromatic nuclei, small nucleoli and scant cytoplasm. Immunohistochemical analysis were immunoreactive to CD3, CD8 & TIA and negative to CD20, CD4 & CD56. Based on clinical findings, histopathology report and immunohistochemical analysis, the patient diagnosed with SPTCL. Hence, any suspicious maxillofacial swelling without obvious sign of infection and trauma shall be investigated until a final diagnosis is reached.

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Published

01.01.2024

How to Cite

Chi Adam, K. B., Jamali, N. R., Harun, N. A., Burhanudin, N. A., & Hamdan, A. H. (2024). Subcutaneous Panniculitis-like T-cell Lymphoma: A Case Report of A Solved Conundrum. IIUM Medical Journal Malaysia, 23(01). https://doi.org/10.31436/imjm.v23i01.1985

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