METABOLIC SYNDROME AND HIGHSENSITIVE C-REACTIVE PROTEIN IN YOUNG HYPERTENSIVE AND PREHYPERTENSIVE ADULTS

Authors

  • Norbaiyah Mohamed Bakrim Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University Malaysia.
  • Aszrin Abdullah Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University Malaysia.
  • Aida Nur Sharini Mohd Shah Department of Emergency and Trauma, Kulliyyah of Medicine, International Islamic University Malaysia.
  • Norlelawati A. Talib Department of Pathology and Laboratory Medicine, Kulliyyah of Medicine, International Islamic University Malaysia.
  • Wan Fatein Wan Omar Department of Basic Medical Sciences, Kulliyyah of Medicine, International Islamic University Malaysia
  • Azarisman Shah Mohd Shah Department of Emergency and Trauma, Kulliyyah of Medicine, International Islamic University Malaysia.

Abstract

Hypertension and prehypertension are reversible risk factors for coronary artery disease (CAD). However, CAD risk is usually inadequately assessed in young adults and underestimated. This study aimed to investigate metabolic syndrome criteria including high-sensitive C-reactive protein (hs-CRP) in young hypertensive and prehypertensive adults. This was a cross-sectional study involving 120 male young adults aged < 45 years old; 40 subjects in control, prehypertensive and hypertensive group respectively. CAD risk factors; body mass index (BMI), waist circumference, lipid profiles, fasting blood glucose and hs-CRP levels were assessed in all subjects. Obesity and hypercholesterolemia were most prevalent in hypertensive, followed by prehypertensive and control group. Mean waist circumference was significantly higher in hypertension than the control (98.3±13.1 vs. 87.0±8.4 cm, p=0.018). Median hs-CRP was significantly higher in hypertension and prehypertension than the control (2.7 vs. 2.2±3.8 vs. 1.1±1.7 p<0.001). The high prevalence of metabolic syndrome and elevation of hs-CRP in young adults with hypertension and prehypertension indicate the increase risk of CAD among these cohorts. Hence, apart from management of high blood pressure, holistic risk modifications strategies such as weight loss, low cholesterol diet and physical exercise are essential to prevent premature CAD.

Acknowledgement: (RIGS 15-076-0076), RMC IIUM.

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Published

2021-04-08

How to Cite

Mohamed Bakrim, N. ., Abdullah, A. ., Mohd Shah, A. N. S. ., A. Talib, N. ., Wan Omar, W. F. ., & Mohd Shah, A. S. . (2021). METABOLIC SYNDROME AND HIGHSENSITIVE C-REACTIVE PROTEIN IN YOUNG HYPERTENSIVE AND PREHYPERTENSIVE ADULTS . INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES, 5(1), 2138. Retrieved from https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/575

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