THE IMMEDIATE EFFECT ON NON-PRESERVATIVE HYALURONIC ACID AND CARBOXYMETHYLCELLULOSE SODIUM (CMC) EYE DROP ON TEAR FILM QUALITY AND PATIENT SENSATION

Abstract

Aims: This study aims to evaluate the immediate effects of non-preservative HA and CMC eye drop on tear film quality and patient’s subjective feedback.

Methodology: In this study, 30 patients were recruited, and each patient were randomly given 2 eye drop. The patients will be evaluated on the conjunctival redness and tear break-up time (TBUT) for each 5, 15, and 60 mins, also for patient’s feedback, questionnaires including Ora Calibra Drop Comfort Scale, Overall Discomfort and 4-symptoms questionnaire will be used.

Results: The TBUT result shows a significant difference between HA and CMC with mean TBUT of 5.17±1.05s for HA and 5.07±1.08s for CMC with (All P < 0.001), and no significance difference were found for both conjunctival redness and patient’s feedback.

Conclusion: HA gives good immediate effect in terms of TBUT compared to CMC, however, other clinical parameters and patient’s feedback showed no significant difference and no improvement between HA and CMC.

Keywords: eye drop, non-preservative, HA, CMC, patient’s feedback