Elevated CA 125 in A Male Patient with Lung Carcinoma: A Laboratory Perspective

Julia Omar; Tuan Salwani Tuan Ismail; Nur Karyatee  Kassim; Aniza Mohammed Jelani

doi:10.31436/imjm.v21i4.1971

Elevated CA 125 in A Male Patient with Lung Carcinoma: A Laboratory Perspective

Authors

Julia Omar Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Tuan Salwani Tuan Ismail Department of Chemical Pathology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Nur Karyatee Kassim Basic Sciences and Oral Biology Unit, School of Dental Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
Aniza Mohammed Jelani School of Medical Sciences Universiti Sains Malaysia Health Campus, Kubang Kerian, Kelantan Malaysia

DOI:

https://doi.org/10.31436/imjm.v21i4.1971

Keywords:

Elevated, CA 125, Male, Lung Carcinoma

Abstract

CA 125 is a tumour marker that is widely used for the management of patients with ovarian malignancy. However, elevated CA 125 has been reported in various non-ovarian cancer patients, including males. This report describes a case of an elevated CA 125 level in a 49-year-old male patient who presented with chronic cough associated with constitutional symptoms. The patient was diagnosed with lung carcinoma based on radiological investigations and tissue histopathological examination. According to recent studies, CA 125 has a potential role as a marker for lung malignancies. However, questions arise about the effectiveness of its measurement for such patients due to its poor specificity and improper utilization of the test. This report focuses on the clinical role of CA 125, the appropriateness of the test request for this patient, the significance of the result, and its implications for the patient and laboratory management.

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Published

01.10.2022

How to Cite

Omar, J., Tuan Ismail, T. S., Kassim, N. K. ., & Mohammed Jelani, A. (2022). Elevated CA 125 in A Male Patient with Lung Carcinoma: A Laboratory Perspective. IIUM Medical Journal Malaysia, 21(4). https://doi.org/10.31436/imjm.v21i4.1971

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Issue

Vol. 21 No. 4 (2022): IIUM Medical Journal Malaysia - October 2022

Section

Case Report

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