Molecular Prevalence of Ent amoeba histolytica and Ent amoeba dispar Infection among Aboriginal Communities in the Southern Region of Perak, Malaysia

Authors

  • Syazwan Saidin Department of Biology, Faculty of Sciece and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjung Malim, Perak
  • Adibah Abu Bakar Department of Biology, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
  • Remmy Keong Bun Poh Department of Biology, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
  • Raja Farhana Raja Khairuddin Department of Biology, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
  • Badrul Munir Md Zain Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, 43600 Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia

DOI:

https://doi.org/10.31436/imjm.v21i1.1740

Keywords:

Molecular prevalence, Entamoeba histolytica, Entamoeba dispar, Entamoeba moshkovskii, Orang Asli

Abstract

INTRODUCTION: In Malaysia, there are little up-to-date data on the prevalence of Ent amoeba spp. and most of the previous studies were carried out using the conventional insensitive method of stool microscopic examinations. MATERIALS AND METHODS: A cross-sectional study was conducted from September 2018 to Mac 2019 in the three villages of Orang Asli communities at Slim River, Perak using the molecular assay. Risk factors associated with Ent amoeba spp. infection was assessed by analysing questionnaire responses obtained from the study participants. RESULTS: From the 55 stool samples collected, molecular prevalence revealed 7.3% and 9.1% E. histolytica and E. dispar infection respectively. Infection was due to indiscriminate defecation and not washing hands after playing with soil or gardening, as well as associated with gastrointestinal symptoms. CONCLUSION: This study showed that there is still an ongoing transmission of Ent amoeba spp. among the studied population, thus warrants the implementation of specific prevention and control strategies of this infection in Malaysia.

Downloads

Download data is not yet available.

Downloads

Published

01.01.2022

How to Cite

Saidin, S., Abu Bakar, A. ., Bun Poh, R. K. ., Raja Khairuddin, R. F. ., & Md Zain, B. M. . (2022). Molecular Prevalence of Ent amoeba histolytica and Ent amoeba dispar Infection among Aboriginal Communities in the Southern Region of Perak, Malaysia. IIUM Medical Journal Malaysia, 21(1). https://doi.org/10.31436/imjm.v21i1.1740