Correlation between schroeder-phase effect and electrocochleography findings
Introduction: In Schroeder-phase masking test, different auditory perception ability towards different phases of Schroeder masker is known as ‘phase effect’. Previously, the phase effect mechanism was proposed to be dominantly contributed by peripheral auditory function, mainly by outer hair cells. This study aims to investigate the possible involvement of central auditory function (i.e. auditory nerve) in the phase effect mechanism. Methods: Four normal hearing and four sensorineural hearing loss subjects were recruited. Schroeder-phase masking test was conducted at 500 Hz, 1 kHz, and 2 kHz (75 dB A), and phase effect was recorded. Electrocochleography (ECochG) test via tip-trode recording using 90 dBnHL tone burst at 500 Hz, 1 kHz, and 2 kHz was also conducted on the same subjects. The amplitude of three ECochG components; i) cochlear microphonic (CM) - arises from outer hair cells, ii) summating potential (SP) - arises from inner hair cells, and iii) action potential (AP)- arises from auditory nerve; were recorded. Pearson and Spearman analysis were performed to find correlation between phase effect and individual ECochG components’ amplitude. Results: Result showed no significant correlation between phase effect and all ECochG components’ amplitude at all tested frequencies with exception at 2 kHz. A significant strong correlation (p: 0.02; r: 0.81) between phase effect and action potential’s amplitude at 2 kHz was observed. Conclusions: This finding suggests that central auditory function (i.e. auditory nerve) is possibly involved in the phase effect mechanism. This finding gives new insight towards better understanding of auditory perception.
How to Cite
All material submitted for publication is assumed to be submitted exclusively to the IIUM Medical Journal Malaysia (IMJM) unless the contrary is stated. Manuscript decisions are based on a double-blinded peer review process. The Editor retains the right to determine the style and if necessary, edit and shorten any material accepted for publication.
IMJM retain copyright to all the articles published in the journal. All final ‘proof’ submissions must be accompanied by a completed Copyright Assignment Form, duly signed by all authors. The author(s) or copyright owner(s) irrevocably grant(s) to any third party, in advance and in perpetuity, the right to use, reproduce or disseminate the research article in its entirety or in part, in any format or medium, provided that no substantive errors are introduced in the process, proper attribution of authorship and correct citation details are given, and that the bibliographic details are not changed. If the article is reproduced or disseminated in part, this must be clearly and unequivocally indicated.