TY - JOUR AU - Ismail, Muhammad Aizat Tamlikha AU - Abdullah Suhaimi, Shahrun Niza AU - Abdul Latiff, Juliana AU - Baharudin, Suraya AU - Azhar Shah, Shamsul PY - 2022/07/01 Y2 - 2024/03/28 TI - A Comparison of Wound Complications and Post-operative Factors Following the Use of Hydrodissection for Mastectomy in Breast Cancer Patients JF - IIUM Medical Journal Malaysia JA - imjm VL - 21 IS - 3 SE - Original Articles DO - 10.31436/imjm.v21i3.2073 UR - https://journals.iium.edu.my/kom/index.php/imjm/article/view/2073 SP - AB - <p><strong>Introduction</strong><strong>: </strong>Mastectomy with axillary clearance remains the hallmark of breast cancer treatment. The conventional use of electrocautery has been associated with the risk of post-operative complications. Hydrodissection may reduce surgery time and produce fewer wound complications with less post-operative pain. The aim of this study was to compare these 2 modalities. <strong>Materials &amp; Methods</strong><strong>: </strong>This prospective randomised control trial was performed with breast cancer patients in Hospital Selayang, Malaysia, between 1 June 2019 to 1 September 2020. The patients were randomised into conventional and hydrodissection groups. The outcomes of interest were post-operative wound complications and other post-operative factors. A chi-square test and independent Student <em>t</em>-test were used to compare the 2 groups. <strong>Result</strong><strong>: </strong>A total of 94 patients were recruited. There was a significant reduction in post-operative seroma in the hydrodissection group compared to the conventional group (40.4 vs 19.1, <em>p</em>&lt;0.05). The surgery in the hydrodissection group was also shorter (114.09 vs 100.15, <em>p</em>&lt;0.05), and there was less 24-hour post-operative pain (3.28 vs 2.13, <em>p</em>&lt;0.05). However, no significant association was observed with other post-operative wound complications (i.e. flap necrosis, surgical site infection and hematoma) or other post-operative factors (i.e. estimated blood loss, mean volume of drain and duration of drain). It was also demonstrated that the hydrodissection technique lowers the risk of developing seroma 3-fold (odds ratio=0.349, <em>p</em>&lt;0.05). <strong>Conclusion: </strong>The use of hydrodissection with liposuction cannula reduced the rate of post-operative seroma and provided a shorter operative duration and better post-operative pain control.</p><p> </p> ER -