@article{R_S_N_2014, title={Conserved Peptide with Therapeutic Potential to Overcome Nasopharyngeal Carcinoma}, volume={13}, url={https://journals.iium.edu.my/kom/index.php/imjm/article/view/490}, DOI={10.31436/imjm.v13i1.490}, abstractNote={<p>Nasopharyngeal carcinoma (NPC) is a squamous-cell carcinoma that arises in the upper lining epithelium of the nasopharynx. In this study, conserved peptide (Ulin-1) of Epstein-Barr virus constructed by Biomodelling and Biocomputation was tested for its ability to stimulate B cells to produce specific antibodies. Spleen cells were isolated and cultured with anti-CD3 and lipopolysaccharide (LPS), and treated or not treated with Ulin-1. Cell culture was harvested six days after incubation and analyzed by flow cytometry. Here, we demonstrated the ability of Ulin-1 to stimulate B cells to produce specific antibodies. The results of this study illustrate the importance of Ulin-1 engineered by Biomodelling and Biocomputation as both active and passive immunization agents against nasopharyngeal cancer.</p>}, number={1}, journal={IIUM Medical Journal Malaysia}, author={R, Muhaimin and S, Widyarti and N, Widodo}, year={2014}, month={Jun.} }