TY - JOUR AU - Ahmad Ramli, Fatin Mardhiah AU - Ramli, Norazsida AU - Mohamed Sideek, Mohamed Arshad AU - Osman, Ilma Syawati PY - 2019/12/26 Y2 - 2024/03/29 TI - EVALUATION OF WOUND HEALING PROPERTIES OF PLECTRANTHUS AMBOINICUS USING HPdLF FIBROBLAST CELL LINES AS STUDY MODEL JF - INTERNATIONAL JOURNAL OF ALLIED HEALTH SCIENCES JA - Inter. J. All. Heal. Sci. VL - 3 IS - 3 SE - Original Articles DO - 10.31436/ijahs.v3i3.318 UR - https://journals.iium.edu.my/ijahs/index.php/IJAHS/article/view/318 SP - 758-758 AB - <p><em>Plectranthus amboinicus</em> is a semi-succulent with pungent oregano odour that belongs to family Lamiaceae. It has been extensively used in traditional medicine for its wound-healing effect. However, there is a lack of scientific evidence to support the claimed. Thus, this study aimed to evaluate wound healing properties of <em>P. amboinicus</em> extracts through <em>in vitro</em> study. Six extracts were used in this study, including three parts of the <em>P. amboinicus,</em> namely, leaves, stem and roots with two types of solvent, aqueous and methanol respectively. Cell proliferation assay was conducted to identify a significant dose that has the potential of wound healing properties. Determined concentration then proceeded with a scratch wound assay for evaluation. Based on the result, it shows that methanol root extract of <em>P. amboinicus</em> with concentration 0.3906 µg/ml has a high potential of wound healing properties in comparison with control. These findings would support the potential use of <em>P. amboinicus</em> as a wound-healing plant.</p> ER -