Anti-lipolytic activity and phytochemical screening ofChelianthesalbomarginataagainst pathogenic microorganisms

  • Rini Jarial UMP

Abstract

ABSTRACT:The aim of the present study was to evaluate the therapeutic properties of selected fern, Chelianthusalbomarginataand to identify its functional compounds. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activities by measuring inhibition zones against a panel of pathogenic bacterial strains using agar diffusion method. MFE at a concentration of 25 μg/ml showed marked anti-bacterial activity against all bacterial strains (6-23mm zone of inhibition) and was maximum against Enterobacter sp (23 mm). In addition, the MFE of C. albomarginatahad the best MIC values of 2.25µg/ml against S. aureus and Enterobacter sp., respectively. The MFE also possessed good anti-lipolytic activity (66.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (79%). This result showed that MFE of C. albomarginataunder optimal concentrationis not only a potent source of natural anti-oxidants and anti-bacterial activity but also possesses efficient cholesterol degradation and anti-lipolytic activities, that is to be beneficial in the body weight management.

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Author Biography

Rini Jarial, UMP
Reseacrh Scholar in UMP

References

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UMP
Published
2017-12-01
How to Cite
Jarial, R. (2017). Anti-lipolytic activity and phytochemical screening ofChelianthesalbomarginataagainst pathogenic microorganisms. IIUM Engineering Journal, 18(2), 56-62. https://doi.org/10.31436/iiumej.v18i2.819
Section
Chemical and Biotechnology Engineering